Reporte de caso
Published on 8 de mayo de 2023 | http://doi.org/10.5867/medwave.2023.04.2664
Successful stem cell transplantation after nelarabine, pegylated asparaginase, vincristine, doxorubicin, and prednisone in refractory early T-cell precursor acute lymphoblastic leukemia: A case report
| Admission | Hyper-CVAD | Clofarabine | FLAG-IDA | Nel Peg-Asp AdmVP | |
| White blood cells [μl] | 56 700 | 8800 | 1000 | 1500 | 1000 |
| Neutrophils [μl] | 2300 | 5500 | 500 | 100 | 100 |
| Lymphocytes [μl] | 1500 | 1600 | 200 | 825 | 800 |
| Monocytes [μl] | 0 | 440 | 0 | 0 | 0 |
| Basophils [μl] | 0 | 160 | 0 | 0 | 0 |
| Eosinophils [μl] | 0 | 0 | 100 | 585 | 0 |
| Red Blood cells [μl] | 4 400 000 | 3 000 000 | 2 500 000 | 2 600 000 | 3 100 000 |
| Hemoglobin [g/dL] | 13.6 | 9.6 | 7.6 | 8.2 | 9.2 |
| Hematocrit [%] | 40.1 | 29.2 | 21 | 23 | 26.4 |
| Platelets [μl] | 10 | 512 | 18 | 40 | 26 |
| Peripheral blasts [%] | 42 | 3 | 0 | 10 | 0 |
| Medular Blasts [%] | 57.9 | 36 | 12 | 59.2 | 0 |
FLAG-IDA, fludarabine, cytarabine, granulocyte colony-stimulating factor, and idarubicin. Nel Peg-Asp AdmVP, nelarabine, pegylated-asparaginase, doxorubicin, vincristine, and prednisone. Hyper-CVAD, Hyperfractioned cyclophosphamide regimen in combination with, vincristine sulfate, doxorubicin hydrochloride (Adriamycin), and dexamethasone.. μl, microliter. g/dL, grams per deciliter.
Source: Prepared by the authors, based on the patient's clinical history at Dávila Clinic.