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Published on November 1, 2012 | http://doi.org/10.5867/medwave.2012.10.5554

Partial exchange transfusion in a patient with homozygous sickle cell disease undergoing heart surgery with cardiopulmonary bypass: a case report

Exanguinotransfusión parcial en un paciente con anemia falciforme homocigota sometido a cirugía cardíaca con circulación extracorpórea: reporte de caso

Deyvis Cruz

Abstract

In patients with sickle cell anemia, the extracorporeal circulation circuit promotes the polymerization of hemoglobin and sickle cell formation. Exchange transfusion reduces circulating levels of hemoglobin S. We report the management of a child with homozygous sickle cell anemia who required surgical closure of atrial septal defect. Partial intraoperative exchange transfusion was performed that decreased hemoglobin S levels from 89% to 23%. Cardiopulmonary bypass was conducted at normothermia with cold blood cardioplegia and the surgical procedure was performed in sinus arrest.

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Authors

Deyvis Cruz

Hospital Regional Universitario Dr. Arturo Grullón
Fundación Corazones del Cibao, República Dominicana

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History

Citation Cruz D. Partial exchange transfusion in a patient with homozygous sickle cell disease undergoing heart surgery with cardiopulmonary bypass: a case report. Medwave 2012;12(10):e5554 doi: 10.5867/medwave.2012.10.5554

Submission date 08/08/2012

Acceptance date 24/09/2012

Publication date 01/11/2012

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Keywords

sickle cell anemia, cardiopulmonary bypass, exchange transfusion

Origin and peer review

con revisión externa por 2 revisores

References

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