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Published on July 31, 2017 | http://doi.org/10.5867/medwave.2017.06.7007

Palliative chemotherapy in metastatic adrenal carcinoma beyond the first line: a case report and literature review

Quimioterapia paliativa tras progresión a la primera línea en el carcinoma suprarrenal metastásico: caso clínico y revisión de la literatura

Luis Cabezón-Gutiérrez , Parham Khosravi-Shahi, Sara Custodio-Cabello, David Ricardo Lujan-Rodríguez, Jesús Ángel Garijo-Álvarez, Claudia María Causso-Lariena, Ana Isabel Franco-Moreno

Abstract

There are no approved therapeutic regimes for adrenal carcinoma following progression to a first line of chemotherapy/mitotane although a high percentage of patients are candidates to receive them. In the present article we review the possible therapeutic alternatives after the progression to a first line of treatment in patients with adrenal carcinoma and we report a case in which a prolonged overall survival is achieved, much higher than expected, probably in relation to the multidisciplinary management of the case and the use of most of the therapeutic arsenal available.

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Authors

Luis Cabezón-Gutiérrez

Departamento de Oncología, Hospital Universitario de Torrejón, Madrid, España

lcabezon@torrejonsalud.com

Calle Mateo Inurria sin número, Torrejón de Ardoz, Madrid, España

Parham Khosravi-Shahi

Departamento de Oncología, Hospital Universitario de Torrejón, Madrid, España

Sara Custodio-Cabello

Departamento de Oncología, Hospital Universitario de Torrejón, Madrid, España

David Ricardo Lujan-Rodríguez

Departamento de Anatomía Patológica, Hospital Universitario de Torrejón, Madrid, España

Jesús Ángel Garijo-Álvarez

Departamento de Cirugía General, Hospital Universitario de Torrejón, Madrid, España

Claudia María Causso-Lariena

Departamento de Endocrinología, Hospital Universitario de Torrejón, Madrid, España

Ana Isabel Franco-Moreno

Departamento de Medicina Interna, Hospital Universitario de Torrejón, Madrid, España

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History

Citation Cabezón-Gutiérrez L, Khosravi-Shahi P, Custodio-Cabello S, Lujan-Rodríguez DR, Garijo-Álvarez JA, Causso-Lariena CMet al. Palliative chemotherapy in metastatic adrenal carcinoma beyond the first line: a case report and literature review. Medwave 2017;17(06):e7007 doi: 10.5867/medwave.2017.06.7007

Submission date 08/05/2017

Acceptance date 16/07/2017

Publication date 31/07/2017

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Notes

Keywords

adrenocortical carcinoma, mitotane, chemotherapy

Origin and peer review

con revisión por cinco pares revisores externos, a doble ciego

References

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