Factors related to mortality in patients with stage 5 chronic kidney disease on dialysis with COVID-19: An exploratory case series analysis

Estudios originales

Published on 29 de diciembre de 2022 | http://doi.org/10.5867/medwave.2022.11.2562

Factors related to mortality in patients with stage 5 chronic kidney disease on dialysis with COVID-19: An exploratory case series analysis

Back to article Table 4

Factors related to mortality: Adjusted and unadjusted odds ratios.

Variable		Bivariate analysis			Multivariate analysis
		OR	95% CI	p	OR	95%CI	p
Sex
	Female	Ref.			Ref.
	Male	1.11	0.91 to 1.19	0.291	1.23	0.48 to 3.17	0.655
Age (years)
	≤ 60	Ref.			Ref.
	> 60	1.01	0.98 to 1.04	0.418	1.02	0.91 to 1.14	0.423
COVID-19 severity
	Mild	Ref.			Ref.
	Moderate	1.92	0.82 to 1.35	0.436	1.21	0.71 to 2.31	0.091
	Severe	1.54	4.51 to 5.23	< 0.001	1.48	2.24 to 7.77	0.042
Body mass index (kg/m2)
	Normal	Ref.			Ref.
	Overweight	1.18	0.88 to 3.48	0.059	1.11	0.49 to 1.84	0.098
	Obese	1.42	1.01 to 6.32	0.111	1.29	1.0 to 5.81	0.213
Lymphocytes cell count x uL
	> 1000	Ref.			Ref.
	≤ 1000	9.01	3.73 to 21.71	0.027	6.88	3.93 to 47.42	0.751
Leukocytes cell count x uL
	≤ 11 000	Ref.			Ref.
	> 11 000	3.8	1.20 to 15.12	0.012	2.58	0.78 to 5.84	0.842
D-dimer mg/L
	≤ 1.5	Ref.			Ref.
	> 1.5	2.87	1.11 to 7.42	0.029	0.67	0.12 to 3.66	0.648
Ferritin mg/dL
	≤ 1000	Ref.			Ref.
	> 1000	3.05	1.22 to 7.06	0.016	2.26	0.81 to 6.31	0.117
CRP mg/dL
	≤ 10	Ref.			Ref.
	> 10	7.73	3.71 to 10.82	0.001	9.72	1.41 to 18.58	0.021
LDH U/L
	≤ 400	Ref.			Ref.
	> 400	6.32	3.12 to 9.07	0.002	4.62	0.49 to 13.38	0.182
HCO₃ mmol/L
	> 20	Ref.			Ref.
	≤ 20	7.58	2.53 to 12.65	0.001	1.23	0.31 to 4.85	0.763
PaO₂/FiO₂ mmHg
	> 150	Ref.			Ref.
	≤ 150	8.31	8.83 to 16.49	0.001	10.23	5.87 to 36.06	< 0.001

AST, aspartate aminotransferase. CRP, C-protein reactive ALT: alanine aminotransferase. IU/L, international units per liter. LDH, Lactate dehydrogenase. PaO₂/FiO₂, arterial oxygen pressure / inspired oxygen fraction. cell/uL, cells per microliter. mg/dL, milligrams per deciliter. mmol/L, millimoles per liter. mmHg, millimeters of mercury.. HCO₃, Bicarbonate. Ref., Reference.

Source: Based on the results of this study.