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Published on 3 de septiembre de 2025 | http://doi.org/10.5867/medwave.2025.08.3081
Temporal analysis of the administration of encephalic reperfusion therapies during the COVID-19 pandemic in a Chilean hospital: An analytical cross-sectional study
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Description of variables.
| NIHSS | Score from 1 to 45 points assigned by a neurologist for the assessment of basic neurological functions in the acute phase of stroke (clinical severity indicator). The dimensions evaluated in the scale are level of consciousness, conjugate gaze, visual fields, facial paresis, upper limb paresis, lower limb paresis, limb ataxia, sensibility, language, dysarthria, and extinction-negligence-inattention. The version with validation studies in Chile was used [ |
| Large vessel occlusion on admission | Results of computed tomography angiography of the brain at the beginning of care. Large vessel occlusion was considered to be the involvement of the MCA in its M1, ICA, and BA segments. |
| Thrombolysis | Administration of thrombolytic treatment to patients with stroke of up to 4.5 hours of evolution. |
| Thrombectomy | Endovascular removal of a thrombus. |
| Mixed therapy | Administration of thrombolytic therapy as bridging therapy and subsequent mechanical thrombectomy in patients with stroke and proximal occlusion of large vessels. |
| Onset-door time | Time in minutes from symptom onset to admission to the adult emergency unit. |
| Door-to-CT time | Time in minutes from the patient’s admission to the adult emergency unit to the first imaging study (computed tomography or magnetic resonance imaging of the brain). Recommended time < 20 minutes. |
| Door-to-needle time | Time in minutes from admission to the adult emergency unit to the start of intravenous thrombolysis. Recommended time < 60 minutes. |
| Start-needle time | Time in minutes from symptom onset to start of intravenous thrombolysis. Recommended time < 120 minutes. |
NIHSS,
Source: Prepared by the authors of this study.