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Published on 3 de septiembre de 2025 | http://doi.org/10.5867/medwave.2025.08.3081

Temporal analysis of the administration of encephalic reperfusion therapies during the COVID-19 pandemic in a Chilean hospital: An analytical cross-sectional study

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Clinical and procedural time differences according to groups.
Prepandemic group(n = 62)Pandemic group(n = 42)p-value
Female46.7% (n = 29)50% (n = 21)0.74(-0.03; 95% CI: -0.16 to 0.22)1
Age (years)66 ± 12.869.5 ± 13.20.17(-3.53; 95% CI: -8.7 to 1.6)2
NIHSS (score)13.5 ± 6.813.5 ± 60.9(0.01; 95% CI: -2.58 a 2.61)2
Presence of major vessel occlusion51.6% (n = 32)MCA M1 75% (n = 24)ICA21.9% (n = 7)BA 3.1% (n = 1)45.2% (n = 19)MCA M1 63.2% (n = 12)ICA 31.6% (n = 6)BA 5.3% (n = 1)0.5(0.06; 95% CI: -0.13 to 0.25)1
Type of therapyThrombolysis 87%(n = 54)Thrombolysis 97.6%(n = 41)0.14
Thrombectomy 6.4%(n = 4)Thrombectomy 2.3%(n = 1)
Combined 6.4%(n = 4)Combined 0%(n = 0)
Start-door time124.1 ± 102.798.3 ± 58.70.14(25.77; 95% CI: -9.02 to 60.56)2
Door-CT time24.3 ± 13.830.2 ± 200.08(-5.86; 95% CI: -12.46 to 0.73)2
Door-to-Needle time58.5 ± 30.468.4 ± 35.10.13(-9.80; 95% CI -22.64 to 3)2
Start-needle time173.4 ± 111.9166.5 ± 67.30.71(6.94; 95% CI: -31.33 to 45.21)2

MCA, Middle cerebral artery. ICA, Internal carotide artery. BA, Basilar artery. NIHSS, National Institutes of Health Stroke Scale. CT , computed tomography.

1 95% confidence interval for the difference in proportions. 2 95% confidence interval for the mean difference.

Results in proportions and averages ± standard deviation. Student’s t and Chi-square were used for the comparison of means and proportions, respectively.

Source: Prepared by the authors based on data from the study.