Editorial

← vista completa

Publicado el 1 de agosto de 2011 | http://doi.org/10.5867/medwave.2011.08.5115

La interpretación de la magnitud de los efectos observados en los ensayos clínicos

Interpretation of the magnitude of the effects observed in clinical trials

Miguel Araujo Alonso

Esta obra de Medwave está bajo una licencia Creative Commons Atribución-NoComercial 3.0 Unported. Esta licencia permite el uso, distribución y reproducción del artículo en cualquier medio, siempre y cuando se otorgue el crédito correspondiente al autor del artículo y al medio en que se publica, en este caso, Medwave.

Autores

Miguel Araujo Alonso

Hospital de Los Andes, Medwave

Figures

Article has no figures.

Foro

No hay mensajes

Historial

Citación Araujo Alonso M. Interpretation of the magnitude of the effects observed in clinical trials. Medwave 2011;11(08):e5115 doi: 10.5867/medwave.2011.08.5115

Envío 27/07/2011

Aceptación 27/07/2011

Publicación 01/08/2011

Article metrics

HTML Views

380

PDF Downloads

20

PDF Download %

5.3%

Total

400

See more

Notas

Referencias

  1. Simon SD. Interpreting negative studies. J Androl. 2001 Jan-Feb;22(1):13-6 | PubMed
  2. van Walraven C, Mahon JL, Moher D, Bohm C, Laupacis A. Surveying physicians to determine the minimal important difference: implications for sample-size calculation. J Clin Epidemiol. 1999 Aug;52(8):717-23. | CrossRef
  3. Fayers PM, Cuschieri A, Fielding J, Craven J, Uscinka B, Freedman LS. Sample size calculation for clinical trials: the impact of clinician beliefs. Br J Cancer. 2000;821:213–219. | CrossRef | PubMed
  4. Wyrwich KW, Tierney WM, Babu AN, Kroenke K, Wolinsky FD. A comparison of clinically important differences in health-related quality of life for patients with chronic lung disease, asthma, or heart disease. Health Serv Res. 2005 Apr;40(2):577-91. | CrossRef | PubMed
  5. Naylor CD, Llewellyn-Thomas HA. Can there be a more patient-centred approach to determining clinically important effect sizes for randomized treatment trials? J Clin Epidemiol. 1994 Jul;47(7):787-95. | CrossRef
  6. Frost MH, Bonomi AE, Ferrans CE, Wong GY, Hays RD; Clinical Significance Consensus Meeting Group. Patient, clinician, and population perspectives on determining the clinical significance of quality-of-life scores. Mayo Clin Proc. 2002 May;77(5):488-94. | CrossRef | PubMed
  7. Barrett B, Harahan B, Brown D, Zhang Z, Brown R. Sufficiently important difference for common cold: severity reduction. Ann Fam Med. 2007 May-Jun;5(3):216-23. | CrossRef | PubMed
  8. Chan KB, Man-Son-Hing M, Molnar FJ, Laupacis A. How well is the clinical importance of study results reported? An assessment of randomized controlled trials. CMAJ. 2001 Oct 30;165(9):1197-202. | PubMed
  9. Faul F, Erdfelder E, Lang AG, Buchner A. G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods. 2007 May;39(2):175-91. | CrossRef | PubMed