Nota técnica

Published on 20 de junio de 2023 | http://doi.org/10.5867/medwave.2023.05.2669

Recommendations for the management of hypokalemia in patients with cancer

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Recommendations for initial dosage and administration of potassium chloride in the outpatient area.
Serum potassium concentration (mEq/L)Peripheral venous catheter scheduleCentral venous catheter schedule
3.0 to 3.5Dose:1 to 2 g of KClPreparation and administration:

1 to 2 ampoules of KCl diluted in 1 liter of physiological solution to be administered in 3 hours

1 to 1.5 g KCl Premix/1000 mL to be administered in 3 hours

Dose:1 to 3 g of KClPreparation and administration:

1 to 3 ampoules of KCl diluted in 250 mL physiological solution to be administered in 2 to 3 hours

1 to 3 g KCl Premix/100 mL to be administered in 2 to 3 hours

2.5 to 3.0Dose:2 to 3 g KCl + 2.5 g MgO4SPreparation and administration:

2 ampoules of KCl + 2 of MgO4S diluted in 1 liter of physiological solution to be administered in 3 hours

3 ampoules of KCl + 2 of MgO4S diluted in 1 liter of physiological solution to be administered in 4 hours.

1 to 1.5 g of KCl Premix/1000 mL to be administered in 3 hours

Dosis: 3 g of KCl + 2.5 g of MgO4SPreparation and administration:

3 ampoules of KCl + 2 ampoules of MgO4S diluted in 250 mL of physiological solution to be administered in 2 to 3 hours

< 2.5ªDose: 3 g of KCl + 2.5 g of MgO4SPreparation and administration:

3 ampoules of KCl + 2 of MgO4S diluted in 1 liter of physiological solution to be administered in 4 hours

Dosis: 3 to 4 g of KCl + 2.5 g of MgO4SPreparation and administration:

3 ampoules of KCl + 2.5 of MgO4S diluted in 250 mL of physiological solution to be administered in 2 to 3 hours

4 ampoules of KCl + 2 of Mg04S diluted in 250 mL of physiological solution to be administered in 3 hours

KCL, potassium chloride. L, liter. MgO4S, magnesium sulfate. g, grams mEq, milliequivalent. mL, milliliters.

ª Evaluate if central administration is necessary (in cases where a dose increase is required due to signs or symptoms of hypokalemia).

Source: Adapted by authors based on Asmar et al., Kim et al., and Pearson et al. [10–12].