Análisis
Published on 26 de febrero de 2024 | http://doi.org/10.5867/medwave.2024.01.2754
Nuevos SNP candidatos para la asociación genética con la enfermedad de Alzheimer: un análisis de desequilibrio de ligamiento para los genes FCGRIIB y PILRA
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Significant LDs between SNPs in FCGRIIB and rs1050501 in super populations.
| rs1050501* | rs13376485 | rs3767640 | rs3767639 | rs3767641 | ||
| (161643798) | (161645877) | (161646116) | (161646120) | (161646112) | ||
| R2 | - | 0.85 | 0.82 | 0.82 | 0.82 | |
| A1 | T (0.75) | G (0.73) | T (0.74) | T (0.74) | C (0.74) | |
| A2 | C (0.25) | A (0.27) | C (0.26) | C (0.26) | T (0.26) | |
| R2 | - | 0.98 | 0.96 | 0.96 | 0.96 | |
| A1 | T (0.75) | G (0.74) | T (0.75) | T (0.74) | C (0.74) | |
| A2 | C (0.25) | A (0.26) | C (0.25) | C (0.26) | T (0.25) | |
| R2 | - | 0.95 | 0.92 | 0.92 | 0.92 | |
| A1 | T (0.86) | G (0.86) | T (0.86) | T (0.84) | C (0.86) | |
| A2 | C (0.14) | A (0.14) | C (0.14) | C (0.13) | T (0.14) | |
| R2 | - | 0.85 | 0.87 | 0.87 | 0.87 | |
| A1 | T (0.86) | G (0.88) | T (0.88) | T (0.88) | C (0.88) | |
| A2 | C (0.14) | A (0.12) | C (0.12) | C (0.12) | T (0.12) | |
| R2 | - | 0.90 | 0.88 | 0.90 | 0.88 | |
| A1 | T (0.91) | G (0.91) | T (0.91) | T (0.91) | C (0.91) | |
| A2 | C (0.09) | A (0.09) | C (0.09) | C (0.09) | T (0.09) | |
R2 = correlation between pairs of loci; A1= allele 1; A2= allele 2. In parenthesis allele frequencies.
Source: Prepared by the authors based on the results of the study.