Notas metodológicas
Published on 6 de junio de 2023 | http://doi.org/10.5867/medwave.2023.05.2704
Approaching the body of evidence: Key concepts of Overviews
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ROBIS tool phases.
| Phase | Title | Brief explanation | |
| 1 | Assess relevance | Optional phase. Consists of assessing whether the target question (defined in PICO terms or equivalent) and the systematic review question coincide. | |
| 2 | Identify concerns regarding the review process. It is divided into four domains | Domain 1: Study eligibility criteria | Consists of assessing whether the eligibility criteria of the primary studies were pre-specified, clear, and appropriate to the research question. |
| Domain 2: Study search and selection | Consists of assessing whether any studies that would have met the inclusion criteria were not included in the review. | ||
| Domain 3: Data collection and study assessment | Consists of assessing whether bias may have been introduced through the data collection or risk of bias assessment processes. | ||
| Domain 4: Synthesis and findings | Consists of assessing whether, given the decision to combine data from the included primary studies, the reviewers used appropriate methods. | ||
| 3 | Bias risk assessment | Consists of assessing the overall risk of bias in the interpretation of the review findings and whether this took into account the limitations identified in the Phase 2 domains. | |
ROBIS, Risk of Bias in Systematic Reviews.
PICO Methodology: Refers to a way of formulating a clinical question based on seeking specific knowledge in the evidence related to its management, prognosis, or other relevant topics. It stands for the acronyms: P: Population of interest; I: Intervention or exposure; C: Control or comparison; O: Outcome/objective or outcome. E.g., In patients with community-acquired pneumonia (P), does amoxicillin with clavulanic acid (I) decrease recovery time (O) compared to macrolides (C)?.