Artículo de revisión
Published on 4 de abril de 2024 | http://doi.org/10.5867/medwave.2024.03.2780
Clinical and radiographic characterization of external root resorption
| Vieira G, 2014 [ | Case-control | Augment of protein DSPP and DPP. | At the time of writing, no molecular diagnostic kits have yet been developed to detect ERR at the clinical level. So far, more high-resolution protein screening methods are still required to identify new molecular markers. MALDI-TOF is the technique of choice for this task. |
| Mavrido A, 2016 [ | Descriptive study | RREC: changes in crown color, periodontal sacs associated with the defect, bleeding on probing, granulomatous tissue. | CER is a dynamic and complex condition involving periodontal and endodontic tissues. Using clinical, histological, radiographic, and scanning microscopic analyses, a better understanding of the evolution of CER is possible. Based on experimental findings, a 3-stage mechanism for the initiation and growth of CER is proposed. |
| Patel S, 2018 [ | Narrative revision | EIRR: crown discoloration change, symptoms of apical periodontitis, negative vital signs. | Accurate diagnosis is required for clinical decision-making, treatment planning, and treatment execution. A CBCT is indicated to confirm the diagnosis and/or aid management. |
| Mona M, 2021 [ | Narrative revision | Increased DMP, DSPP, and its functional domains (DPP and DSP), inflammatory markers such as TNF-α, IL-6 and IL1-β and MicroRNA-29. | The field of proteomic biomarkers is relatively new in dental disorders. Such a diagnostic approach has excellent potential to avoid unnecessary invasive procedures. It has promising uses and may significantly impact the healthcare system. |
| Kapoor P, 2022 [ | Bibliographic revision | Increase in dentin proteins, enzymes, and protein metabolites. Decrease in IL-1α. | Several biomarkers in biofluidics indicate active resorption, while the severity of resorption was associated with DSPP and GM-CSF in GCF, as well as some salivary proteins. However, a robust study design is mandatory in the future. |
Abbreviations. ERR, external root resorption. MALDI-TOF, two-dimensional electrophoresis followed by mass spectrometry. DMP, dentin matrix acid phosphoprotein. DSPP, dentin sialophosphoprotein. DPP, dentin phosphoprotein. TNF-α, tumor necrosis factor-alpha. IL-6, interleukin-6. IL-1β, interleukin-1beta. IL-1α, interleukin-1 alpha. EIRR, External inflammatory root resorption. CBCT, cone beam computed tomography. CERE, cervical external root resorption. SERR, superficial external root resorption. CER, external cervical resorption. RERR, replacement external root resorption. TAR, transient apical resorption. GM-CSF, Granulocyte Macrophage Colony Stimulating Factor. GCF, Gingival crevicular fluid.
Source: Prepared by the authors.