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Daily compliance of the ABCDEF liberation bundle for patients in the intensive care unit: A retrospective descriptive study

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Clinical and sociodemographic characteristics of patients admitted to the ICU (n = 133).
VariableTotaln (%) or P50 (IQR)(n = 133)IMVn (%) or P50 (IQR)(n = 63)Without IMVn (%) or P50 (IQR)(n = 70)
APACHE II at ICU admission (n = 78)113 (9 to 18)13 (10 to 22)11 (7 to 15)
Age (years)53 (39 to 67)54 (41 to 64)51 (35 to 71)
Gender
Female57 (43)31 (49)26 (37)
Male76 (57)32 (51)44 (63)
Body mass index (n = 59)228 (26 to 39)30 (25 to 39)27 (23 to 29)
Comorbidities
045 (34)25 (40)20 (29)
131 (23)13 (21)18 (26)
224 (18)12 (19)12 (17)
≥ 333 (25)13 (21)20 (29)ICUICU
ICU length of stay, days5 (3 to 9)9 (4 to 15)3 (2 to 5)
Duration of IMV, days3 (1 to 8)3 (1 to 8)N/A
Duration of sedation, days (n = 78)4 (2 to 11)6 (3 to 12)2 (1 to 4)
Type of sedation
Opioids61 (78)57 (93)4 (23)
Benzodiazepines58 (74)44 (72)14 (82)
Dexmedetomidine50 (64)43 (70)7 (41)
Propofol43 (55)42 (69)1 (6)
Antipsychotics24 (31)18 (29)6 (35)
Ketamine22 (28)22 (36)0 (0)
Neuromuscular blocking agents24 (31)24 (39)N/A
Previous unit
Emergency service51 (38)18 (29)33 (47)
Transfer from another healthcare facility48 (36)23 (37)25 (36)
Intermediate care unit25 (19)16 (25)9 (13)
Ward7 (5)6 (10)1 (1)
Other2 (2)0 (0)2 (3)
Pathology of admission
Cardiac23 (17)10 (16)13 (19)
Respiratory22 (16)10 (16)12 (17)
Neurological21 (16)8 (13)13 (19)
Sepsis19 (14)13 (21)6 (8)
Gastrointestinal13 (10)5 (8)8 (11)
Polytrauma10 (8)7 (11)3 (4)
Suicide attempt8 (6)2 (3)6 (9)
Others17 (13)8 (13)9 (13)
Discharge destination
Transfer to intermediate care94 (71)47 (75)47 (67)
Discharge from ICU16 (12)4 (6)12 (17)
ICU mortality8 (6)8 (13)0 (0)
Transfer to medical-surgical ward8 (6)4 (6)4 (6)
Transfer to another center6 (5)0 (0)6 (9)
Transfer to the maternity ward1 (1)0 (0)1 (1)

APACHE II, Acute Physiology and Chronic Health disease Classification System II. IQR, Interquartile range. ICU, Intensive care unit. IMV, Invasive mechanical ventilation. N/A, Not applicable. P50, Median.

1APACHE II was obtained from 78 patients, of whom 49 were with IMV and 29 without IMV.

2Body mass index was obtained from 59 patients, of whom 35 were with IMV and 24 without IMV.

Corresponds to a medical/surgical ward and an admission from another ICU.

Benzodiazepines are considered both enteral and intravenous.

Type of sedation: percentages calculated considering the 78 patients who received sedative drugs.

78 patients received sedation, of whom 61 received IMV, and 17 did not receive IMV.

Source: Prepared by the authors based on data extracted from electronic clinical records.