Estudios originales

Fulvestrant in clinical practice: Effectiveness analysis in Uruguayan patients with HR+/HER2- breast cancer

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Multivariate analysis of factors associated with OS.
Hazard ratiopAdjusted hazard ratio
Age
 < 65aa
 ≥ 651.100.1511.150.063
Sex
 Maleaa
 Female1.050.8731.040.905
Origin
 Montevideoa
 Rest of the country0.980.726
Health care provider
 Privateaa
 Public0.790.01850.820.063
 Functional statusa
 0a
 a1.51<0.001
 22.020.007
Bone metastasis a
 Noaa
 Yes1.260.0061.210.035
Lung metastasis
 Noa
 Yes1.080.322
Hepatic metastasisa
 Noa
 Yes1.60<0.001
Cutaneos/subcutáneos metastasis
 Noa
 Yes0.840.080
Central nervous system metastasis
 Noa
 Yes1.210.446

OS, overall survival.

aPerformance status and presence of liver metastases variables were used to stratify the model because they showed non-proportionality in the risks.

Source: Prepared by the authors of this study.