Estudios originales
Published on 26 de junio de 2025 | http://doi.org/10.5867/medwave.2025.05.3037
Descriptive analysis of immunological abnormalities in recurrent reproductive failure and therapeutical outcomes
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Baseline clinical data of the sample.
| Age (years) | 37.7 (±3.8) | 38.3 (±2.8) | 36.3 (±3.3) | 34.5 (±5.9) | 35.9 (±3.1) | 37.5 (±4.2) |
| Number of miscarriages | 2.7 (±1.3) | 0.6 (±0.7) | 0.0 (±0.0) | 1.0 (±0.5) | 0.18 (±0.3) | 1.97 (±1.5) |
| N° of stimulation cycles (IVF) | 0.9 (±1.7) | 2.0 (±1.3) | 1.2 (±1.5) | 0.6 (±1.7) | 0.2 (±0.3) | 1.15 (±1.6) |
| N° of good quality embryo transfers | 1.1 (±1.8) | 2.8 (±2.4) | 0.5 (±0.8) | 1.0 (±2.6) | 0.09 (±0.03) | 1.48 (±2.1) |
| N° of oocyte donations | 0.1 (±0.7) | 0.3 (±1.2) | 0.0 (±0.0) | 0.0 (±0.0) | 0.00 (±0.0) | 0.20 (±0.8) |
| Smoking (%) | 17 (9.8%) | 9 (12.8%) | 1 (12.5%) | 0 (0.0%) | 0 (0.0%) | 25 (9.3%) |
| FH autoimmune disease (%) | 40 (22.8%) | 16 (23.3%) | 5 (55.5%) | 2 (28.5%) | 8 (61.5%) | 70 (25.7%) |
| BMI > 25 (%) | 45 (25.4%) | 27 (38.8%) | 2 (22.2%) | 1 (16.6%) | 3 (42.8%) | 77 (28.0%) |
| BMI < 18 (%) | 7 (4.3%) | 2 (2.7%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 9 (3.4%) |
| FH autoimmunity (%) | 47 (26.3%) | 15 (21.6%) | 3 (33.3%) | 2 (28.5%) | 8 (61.5%) | 74 (26.7%) |
| FH recurrent reproductive failure (%) | 30 (16.9%) | 4 (6.6%) | 0 (0.0%) | 4 (57.1%) | 4 (30.7%) | 41 (14.8%) |
| PH cardiovascular (%) | 55 (30.9%) | 22 (31.6%) | 2 (22.2%) | 2 (28.5%) | 6 (46.1%) | 84 (30.3%) |
BMI, body mass index. FD, fetal death. FH, family history. I, infertility. PG, preventive group.RM, recurrent miscarriage. RIF, recurrent implantation failure. PH, Personal history.
Mean ± standard deviation. Frequencies are shown as absolute numbers (%).
Source: Prepared by the authors based on the results of the study.